Showing posts with label consumer traits. Show all posts
Showing posts with label consumer traits. Show all posts

Thursday, January 20, 2022

Salmon, apples and potatoes — 3 healthy and sustainable foods that you can buy now under the new “bioengineered” label

Label required by Jan. 1, 2022, on food products containing bioengineered products and byproducts. Credit: USDA.

Label required by Jan. 1, 2022, on food products containing bioengineered products and byproducts. Credit: USDA.

(this post originally appeared on Genetic Literacy Project - January 4, 2022

The “bioengineered” label for foods sold in the United States is now in effect. Any food or food ingredient that has been genetically modified must include a label that says “bioengineered,” or come with a phone number or QR code guiding consumers to more information online.

On the positive side, the national labeling law avoids the nightmare of state-by-state requirements. The major negative is that the label could well become the target for negative campaigning and marketing around the fear-based, anti-GMO narrative and misleading “Non-GMO” labeling that have permeated food-related messaging for so long.

Fortunately there are some exciting “consumer-oriented” products finally becoming available which can display that newbioengineered label that would help consumers to overcome the disinformation and embrace technologies that actually improve our food system and our ability to enjoy it. The most notable are non-browning Arctic Apples, non-browning Innate potatoes and healthy, fast-growing, AquaBounty Salmon, which I wrote about two years ago in an article in Forbes and on Medium titled: “Three Foods I Wish I Could Buy at Costco.” These novel options that are not only tasty and healthy, but also have benefits in terms of sustainability, climate-smart farming, and food waste reduction.

I’ll discuss each example in detail below, but the big picture is that consumers in some locations are now able to find these products for sale, although they are not yet in national chains like Costco or Walmart, which for now are bowing activist pressures. Supplies are limited, but there is also a hesitancy on the part of many retailers who don’t want to be “first” to step into something potentially controversial. The truth is that there is no justification for such controversy since all the safety or environmental questions have already been addressed during the extraordinarily long and rigorous regulatory process overseen by the USDA, EPA and FDA. The farmers that grow major commodity crops have been able to take advantage of biotech crops for a long time, but consumers and specialty crop growers are only beginning to have that opportunity. Let’s see what that looks like.

Arctic Apples

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Twenty-five years ago a Canadian fruit grower named Neal Carter and his wife Louisa started a project to develop non-browning apples with the vision of reducing food waste and reversing the declining consumption of that healthy fruit. With a very small organization (e.g. less than 12), Okanagan Specialty Fruits Inc.(OSF) developed varieties of well known apple cultivars in which a gene for a particular enzyme was turned off or “silenced.” That enzyme is what turns the fruit brown when it is bruised or cut. Turning it off makes the fruit more robust in general and dramatically reduces the amount that is rejected from harvest through storage and processing. The other non-browning trait advantage is that Arctic apples can also be sold as a ready-to-eat, sliced product that retains the fruit’s full flavor, aroma and vitamin content.

OSF shipped me a box of these as whole apples a few years ago and I was able to take them to a potluck dinner a couple of hours after slicing and compare them with regular apples. Everyone who tried them thought they were great, wanted to be able to buy them, and didn’t worry at all about them being “GMO.” I think that will be a normative reaction once consumers can see biotech advantages first-hand instead of just hearing them demonized by notorious anti-technology groups and writers.

OSF was acquired in 2014 by Intrexon, a publiccompany where R.J. Kirk served as Chairman and CEO. As of 2020 ownership transferred to Third Security, LLC, a venture capital firm led by Kirk. Kirk encouraged a vertical integration business strategy focused on the sliced apple or “Fresh cut” market. Neal Carter continued to run the company as he still does today. Talking with him last week I was impressed by the scope of his expertise and understanding ranging from the growing the trees to the processing step, to nutritional information, food safety protocols, product distribution options, marketing and building of a solid public image. He also has a solid understanding of the science involved in the genetics of the Arctic® offering and how that technology has become ever more sophisticated over time.

OSF has purchased or leased 1300 acres of land for apple production land in Washington State where it currently grows 2.6 million trees. They have plans for additional orchards and their own dedicated slicing facility in the near future. Their apple variety options include Arctic Goldens, Arctic Grannys, and as of this year Arctic Fuji. Arctic Galas will be next. In the longer term, non-browning red skinned apples are on the list. They are also hoping to develop more robust, non-browning cherries that will avoid the stem decline or pitting that tends to occur with that delicious fruit.

Credit: Articapples.com

OSF’s apples are now being sold asstand-alone slices or as a component of fruit mix products packaged in cooperation with companies providing the other ingredients. There is also a dried version which is special because the slices don’t require sulfur products to prevent browning while they were being dried. These products are increasingly available at some regional grocery retailers; at certain convenience store chains and food service outlets. Some is now provided through military procurement. In some geographies the sliced fruit is now available for home delivery from Amazon Fresh. The convenience store and home delivery options have become even more popular during the pandemic. In the long term these slices might be found at a Costco or other national chains, but this will require expanding orchard plantings that that is a relatively slow process (4-5 years from planting to achieve full productivity).

Overall, Arctic apples address many societal needs and desires: a positive olfactory experience (flavor, aroma, appearance, and texture), convenience, health benefits, food waste reduction, and efficient use of farmland and inputs.

Innate Potatoes

In the process of harvesting, cleaning, sorting and storage of potatoes, they can get bruised leading to black spots and browning inside the potato that makes them ugly and undesirable. This damage generates substantial waste all along the food chain from the packing house, to processors, to stores and through to the consumer. Black spots and browning are also very undesirable for making something like hash browns at home.

The Simplot potato company has been using biotechnology methods to “turn off” or “silence” a PPO gene that is similar to the one silenced in Arctic Apples. They have also turned off genes to reduce the amount of the amino acid asparagine in the potatoes that can turn into the naturally occurring compound acrylamide during frying. Acrylamide is linked to various health effects so having less is a nice outcome. These potatoes have been on the market since 2015 as “white russets” and were labeled as “bioengineered” even before the requirement to do so in 2022. This has not been controversial with the consumers who have had access to the product, mainly at regional grocery chains and restaurants, not in national chains like Costco, Safeway, Kroger, etc. Again this is partly because of retailer’ hesitancy to “be first,” but as the supply of these potatoes increases it will be interesting to see whether that picture can change

Simplot has other grower- and consumer-oriented potato improvements in the development pipeline. They have moved genes from wild potatoes to make their potato cultivars more resistant to late blight – a fungal disease that caused the Irish potato famine in the 19th century and which still requires substantial control efforts by potato farmers today. That trait is “cisgenic” or “intragenic” in that it is based on potato genes being used in potatoes.

Simplot also added these resistance genes to the potato cultivars typically grown in Bangladesh and Indonesia and provided them for free to those farmers. They are also working on resistance to a virus disease (Potato Virus Y) which has become a bigger issue for North American potato farmers since an insect called the potato psyllid has moved into the Northwest. That pest movement has likely enabled by climate change in that pest can now survive the warmer winters in that major growing region. Hopefully, the anti-technology voices won’t deprive the farmers of these pest resistance traits as they did successfully with the Colorado potato beetle resistance trait developed by Monsanto and first sold in 1997. Growers saw great benefit from those “NewLeaf Potatoes,” but the controversy led to their removal from the market in by 2001.

Simplot has future plans to use CRISPR on russet varieties and even extend them on smaller, non-Russet potatoes. They recently announced they are working with the strawberry breeding company, PSI to make various consumer-oriented options in that popular fruit crop using gene editing. Simplot has also received a CRISPR license to work on browning and bruising reduction for avocado! That could prevent a lot of food waste at the consumer level.

The many sustainability advantages of Innate non-browning potatoes. Credit: Simplot Biosciences

Overall the Simplot efforts address many positive societal benefits: food waste reduction, enhanced consumer experience, health benefits, farmer pest management and land-use-efficiency.

AquaBounty Salmon

The third food is a kind of Atlantic salmon that has been improved using biotechnology so that it can grow more rapidly and require less feed while still having the highly desirable nutritional content of other salmon (e.g. the heart-healthy omega-3 fats). The US imports ~400,000 metric tons of farmed Atlantic salmon each year, around 16% of the growing global demand (Norway, Chile, Canada and Scotland are the largest producers).

AquaBounty salmon are raised in bio-secure, re-circulating, terrestrial aquaculture systems (RAS) that return 95% of the water each day and remove any sludge for use as fertilizer on nearby farms. In the tanks the fish can be carefully monitored. They are also free from the parasites and pathogens found in the ocean so they don’t need antibiotics or vaccines. Another advantage is that they are not exposed to ocean pollutants like heavy metals or microplastics.AquaBounty salmon can be raised anywhere such a facility can be built – the first one is in near Muncie Indiana so the transport carbon footprint is minimized to many US markets vs international imports.

Salmon swimming in tank. Credit: AquaBounty

While this desirable fish option is now commercially available for some Americans and Canadians, it will take time to expand the number of production facilities sufficiently to serve national food retail chains like a Costco. Unfortunately my home state of California might never be on the list for local production. There is a state regulation against raising these “GMO” fish. There is no rational reason; it isn’t that there is danger of these fish getting loose in the Pacific Ocean (they are all sterile females and the tanks are secure). I’m still trying to trace the “logic” here, but ironically there is an exception in the state law for aquarium hobbyists to buy novelty “Glofish” that are genetically engineered to glow because they have DNA from jellyfish.

It makes no sense to allow anyone to buy cool“GMO” pets and not allow local production of one of the most resource efficient, environmentally friendly, safe, healthy and delicious food production options that will eventually be available to most regions.

What’s next?

If you want to know more about the label, and which foods or ingredients will be labeled as such, check out the USDA website and hear a good discussion featured in the first part of this podcast.

If you as a consumer are excited about these options and would like to see more innovative food products in the future, I would encourage you to seek them out in stores or on-line and to ask for them at your favorite retailers. Our best hope of overcoming the decades-long, fear-based campaigns against modern biotechnology is to finally “vote with our food dollars” and let our voice be heard through the comment boxes or websites that are available.

Friday, October 21, 2016

Could The Humble Potato Change Your Image of GMOs?

Hash browns cooking - regular potatoes on the left and the new "White Russet" biotech potatoes on the right
Last week I got my first chance to cook with a "GMO" Potato.  I made one of my favorite breakfast dishes - hash browns!  I was excited to try that with these new potatoes because they have been modified to turn off the gene for the enzyme that makes them turn brown when cut (polyphenol oxidase), or in this case grated.  With regular potatoes, even if you work quickly, the grated potatoes begin to darken before you can get them into the pan.  I've gotten around that by grating them directly into the hot oil, but that is far from ideal in terms of safety.  With these new potatoes I had plenty of time to grate them and shape them.  They turned out not only looking far better, but also came out crispier and better tasting.  It is going to be difficult to put up


These potatoes have been approved for sale and are in many stores, but are not yet in stores where I live.  Colleagues at Simplot Biosciences were kind enough to mail me a bag.  I also posted a video about using this excellent new product.  There is a next generation of potatoes going through the USDA deregulation process.  In addition to the traits that reduce food waste (non-browning/bruising, low sugars in storage) and enhance food safety (reduced acrylamide production during frying), the latest potatoes also have a gene from wild potatoes that makes them resistant to a disease called late blight.  That is what caused the Irish Potato Famine in the 19th century and an issue for potato growing to this day.  The following is the comment I submitted to the USDA in support of deregulation:

(Submitted to USDA on 10/11/16 - https://www.regulations.gov/docket?D=APHIS-2016-0057)

I am writing to support the deregulation of the X17 and Y9 potato lines which involve the same modifications as in previously deregulated lines.  Potatoes are a difficult crop to breed because they only rarely make seed and are polyploid.  While new lines are being developed, there is a substantial advantage of being able to modify older varieties that have proven field performance and desirable characteristics for cooking.  In this case the modified lines are Ranger Russet and Atlantic which are both important commercial varieties.

As with earlier lines, the RNAi gene silencing mechanism has been used to reduce the potential for acrylamide formation during cooking, reduce sugar production during storage which lowers quality, and reducing bruising and browning.  Together the last two traits will help to reduce food waste.  I believe that consumers will also find these potatoes to be quite desirable.

This week I had the chance to cook some of the Russet Burbank cultivar with this non-browning/bruising trait.  I like to make hash browns with fresh potatoes but because of the browning issue I have to grate the potatoes directly into the hot oil.  With these modified potatoes I was able to grate the potatoes and form them into servings prior to frying.  The non-modified potato I used for comparison was definitely inferior in terms of appearance and taste (I've included a picture of the hashbrowns - the upper one is with a standard potato and the lower one is with the down-regulation of the polyphenol oxidase gene.  I will certainly be looking forward to seeing more of these potatoes in commercial channels.

Top hashbrown from a standard Russet Burbank, lower from a White Russet, modified version.


Some critics have implied that the RNAi gene silencing mechanism could have unintended effects.  I believe that this discussion developed by Food Standards Australia New Zealand does an excellent job of debunking the paper by Heinemann et al which is often cited in this context.  Small double stranded RNAs are abundant in the food supply and this mechanism of gene regulation is widespread among eukaryotes.

As a plant pathologist I am particularly excited about one of the traits included in these new potato lines - resistance to the late blight fungus, Phytopthora infestans.  Not only did that disease cause the Irish Potato Famine in the 1800s, it represents a major management burden for potato growers around the world today.  To be able to include plant resistance in an integrated control program will be extremely helpful for potato growers.  The gene, VNT1, comes from wild potatoes native to South America.  To move that gene through conventional breeding would be slow and it would be very difficult to get back to the horticultural and culinary characteristics of desirable potatoes like Ranger Russet or Atlantic. This is an extremely logical application of modern biotechnology and one that would make a great deal of sense for other crops like grapes or coffee which also have pools of genetic diversity which are hard to utilize using conventional or even marker-assisted breeding.

To conclude it makes perfect sense to deregulate this crop as it presents no plant pest risk and substantial societal benefit in terms of food waste reduction and disease management.




Friday, August 26, 2016

Another Biotech Apple That Can Help Change The Conversation About "GMO Crops"

A picture of the Arctic Granny that appeared in a great article in the trade magazine, Growing Produce last year.


Non-browning apples and potatoes are part of a second wave of biotech crop improvements which I believe will change the public conversation about "GMO crops" in a positive way.  A third Arctic Apple cultivar (Fuji) is currently going through the USDA deregulation step which will open the way for commercial production over the next few years.  Apparently the public comments to USDA have been overwhelmingly positive.  I decided to add my own comment because I've had the opportunity to meet the great folks at Okanagan Specialty Fruits who developed these apples, and the folks at Intrexon who are supporting the commercial phase.  I am very impressed with what they have accomplished and the plans they have for bringing these great products to consumers.

I've copied below the text of the comment I submitted to USDA today.  If you would like to comment you can do so at this link:

https://www.regulations.gov/comment?D=APHIS-2016-0043-0001


My Comment to USDA About The Arctic Fuji, Non-Browning Apple


"I am writing in full support of this particular deregulation of the Arctic Fuji apple.  I do this as an agricultural scientist, as a long-term observer of crop biotechnology (40 years), as a consumer, and as a grandfather.  USDA-APHIS is completely justified in concluding that this RNAi-based, non-browning trait represents no "plant pest issues" so that commercial planting can proceed.  The "genetic contamination" issue that is sometimes raised is meaningless for a crop like apples that is never grown from seed but which is vegetatively propagated and which is commonly pollinated with crab apple.  Pollen movement presents no problems for apple growers or for consumers.  As a plant pathologist I concur with the conclusion from field tests which indicate that the trait has no effect, positive or negative, on the pest resistance profile of apples.

What this trait does provide is a combination of food waste reduction and opportunities for desirable consumer options such as full flavor and aroma sliced apples, no-sulfite dried apples and, use in smoothies etc.  I've tasted examples of all these uses with previous cultivars and can highly recommend them to my fellow consumers.

I have had the opportunity to share a box of a previously deregulated cultivar, Golden Delicious, with friends at a pot luck dinner last November.  I offered slices that had been prepared 4 hours before the event and showed how they were still white and aromatic while the conventional slices were browned to the point that no one wanted to take more than one comparison taste.  The non-browning Arctic apples truly "changed the conversation about GMOs" because it was a concrete example of how biotechnology can provide a meaningful consumer trait.  As Fuji is my favorite apple variety I am particularly enthused about being able to buy and share this next cultivar when the production is ramped up.  As many children do, my grand daughter loves apples, and I see this product as a way to further encourage that healthy inclination.

I fully realize that some of our international trading partners have irrational and problematic attitudes about biotech crops, but with a fully "identity preserved" crop like apples, there should not be a risk to our export business.  I am confident in the plan that OSF and Intrexon have for stewarding the main sliced product line and the co-product lines.  I believe that a timely deregulation of this and subsequent cultivars will send the appropriate message to the global market for apples.

Finally, I believe that this trait demonstrates that even a small commercial entity can navigate both the technological and regulatory path to biotech product development.  The vast majority of the work even with this cultivar was done by a company with around 8 employees!  While our system would benefit by some stream-lining and greater emphasis on product over process, this remains an important precedent.

So again, I want to express my whole-hearted support for this deregulation decision.

Steve Savage, Ph.D."

My grand daughter holding a Fuji apple she picked in
my yard a couple of years ago (unfortunately the browning kind)
You are welcome to comment here and/or to email me at savage.sd@gmail.com